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The main reason is that the large amount of extracellular matrix deposition in the ovarian cancer microenvironment leads to tumor vascular collapse, reduced vascular perfusion, poor drug delivery and blocked migration of cytotoxic T cells to the tumor area (139)

Classical Complement and Inflammasome Activation Converge in CD14highCD16- Monocytes in HIV Associated TB-Immune Reconstitution Inflammatory Syndrome

Metabolic dysregulation Multiple metabolic abnormalities have been implicated in the pathophysiology of ME/CFS

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