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Description
Karyopherin 1 is essential for all nuclear import by karyopherin proteins and depletion of this factor may dramatically reduce the transport of cargo by karyopherin-based transport
These enzymes are rate-limiting in the production of ceramides, which constitute approximately fifty percent of the intercellular lipid matrix and are absolutely essential for maintaining barrier impermeability
However, serine and threonine residues are highly distributed in PrLD
10.1021/ar010129t
