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10.3390/antiox10030383 5 ChangY.JeongS

Alterations in NK cells, T regulatory cells (Tregs), Th17, and Th1/Th2 ratio may be associated with pregnancy-related complications, pregnancy loss, implantation failure, and preeclampsia (92)

This disruption may be attributed to the absence of the 21.5-kDa isoform of myelin basic protein (MBP) (Sugiyama et al., 2002) or age-related dysregulation of cyclic nucleotide phosphodiesterase (CNP), two proteins that are vital for the formation and maintenance of paranodes

Because of the difficulty of obtaining complete urine collections, creatinine clearance calculated in this way is at least as reliable as estimates based on urine collections