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This trial consisted of two parallel multi-center studies, targeting different SMA cohorts (Clinicaltrials.gov ID NCT00227266)

10.1016/j.scitotenv.2018.06.084 [DOI] [PubMed] [Google Scholar] Wu X., Chen L., Zeb F., Huang Y., An J., Ren J

This leads to the formation of regenerative hepatic nodules encased in dense fibrous tissue, containing significantly higher levels of extracellular matrix proteins, particularly collagen types I, III, and IV, which hinder portal blood flow and elevate portal pressure, ultimately culminating in clinically significant portal hypertension in later disease stages (1)

[21] measuring TPV, we estimated the standard deviation of the % change in TPV to be 11%