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Gimsing P, Hippe E, Helleberg-Rasmussen I, et al
Expression and function of multidrug resistance transporters at the bloodbrain barriers

The Food and Drug Administration-approved -blocker carvedilol offers a significant therapeutic advantage in HF because of its ability to activate signaling downstream of - Arr (Bond et al., 2019

The enzyme catalyzing this step was later identified as a mitochondrial dehydrogenase (ba et al., 1995), in a difference to the animal pathway, in which the last step is catalyzed by an oxidase associated to the microsomal fraction
