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However, pharmacodynamic studies in patients using nasally administered hGH did not induce increased levels of IGF-1, and hence, these formulations were considered therapeutically inactive (4)
BPC-157 has been observed to interact with the nitric oxide (NO) system and to upregulate growth hormone receptor expression in tendon fibroblasts

Zarei, M., Sprenger, A., Metzger, F., Gretzmeier, C

Phase I, II and III trials in inflammatory bowel diseases: a practical guide for the non-specialist
