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From this class, prostaglandin-D 2 synthase and prostaglandin-E 2 synthase catalyze the cleavage of prostaglandin H 2, forming prostaglandin-D 2 or E 2 [216]

10.1016/j.tem.2019.03.003 17 BersukerK.HendricksJ

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The subsequent decrease in GSH:GSSG ratio has consequences for MGO detoxification and the redox status [65], which may ultimately alter BBB permeability
