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doi: 10.1016/j.jaca dv.2025.101599 Varshitha T Panduranga, Maureen Masara, Adam Kurnick, Varsha Talanki, Harshith P Chandrakumar, Siddharth Dubey, Sabu John

Many of these effects have been shown to persist beyond acute withdrawal, and this dopamine hypofunctional state has been suggested to underlie, in part, the negative affect and dysphoria associated with protracted abstinence, as well as the motivation to re-engage in alcohol-drinking behavior (Diana, 2011