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Belmont, CA: Wadsworth, Cengage Learning.

Further, the process of the present invention provides advantages, such as environmental friendliness due to the use of an immobilized enzyme in the preparation of the intermediate, and applicability thereof to industrial-scale production arising from decreased production costs due to the recyclability of the enzyme

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Interestingly, succinate supplementation also phenocopied decreased KG in its ability to inhibit proliferation of CCNE1-driven cells in the presence of DNA damaging agents and was rescued by KG supplementation ( Fig