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Disc degeneration is characterized by oxidative-stress-driven apoptosis (cell death) and senescence (cell aging) of nucleus pulposus mesenchymal stem cells

It is worth noting that a breakthrough clinical trial was launched in Japan in 2018 to transplant allogeneic human iPSC-derived dopaminergic neuronal precursors into the striatum of patients with PD [9, 41]

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After the administration of l-carnitine, we found that the high- and low-dose l-carnitine groups also exhibited significantly improved sperm motility rates, sperm counts and sperm abnormality rates in a hypoxic environment, and the high-dose group also improved the percentage of forward movement in sperm
