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however, activated microglia can increase BBB permeability and vascular leakage (Haruwaka et al., 2019), potentially through the release of proinflammatory mediators and generation of ROS

Pharmacol Ther 73:121146 Zhong Z, Wheeler MD, Li X, Froh M, Schemmer P, Yin M, Bunzendaul H, Bradford B, Lemasters JJ (2003) L-Glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent

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