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First, the risk profile of patients enrolled in the RCTs does not necessarily match that of patients for whom we are considering weighing the long-term benefits and potential harms

"Effects of insulin-like growth factor-I and LR3IGF-I on regional blood flow in normal rats." Journal of Endocrinology 155.2(1997):351-358

Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis

Options that many people find well tolerated include: Boiled or mashed potato (without heavy cream or butter) White rice or plain pasta in small quantities Soft-cooked vegetables such as courgette, carrots, and spinach Porridge oats are nutritious but contain moderate fibre