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The perforin and granzymes induce apoptotic cell death by different pathways, such as caspases-3/7 activation, cytochrome C release from mitochondria and IL-1 regulation by caspase-1

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Research identified that the 176191 region plays a key role in: Fat breakdown (lipolysis) Inhibition of lipogenesis (fat formation) Metabolic regulation AOD-9604 is a stabilized version of this fragment with enhanced biological activity and no direct GH or IGF-1like growth effects