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Biol Trace Elem Res 26(1):629635 Renaudin C (1999) Slnium: action, toxicit et utilisation en thrapeutique, Thse pour le doctorat de Pharmacie de lUniversit de Poitiers Robberecht HJ, Hendrix P, Van Cauwenbergh R, Deelstra HA (1994) Actual daily dietary intake of selenium in Belgium, using duplicate portion sampling

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showed that, in mice, thiamine deprivation for 14 days led to different degrees of enzymatic deficiencies when testing for TKT, PDH, and KGDH activities in the cortex and hippocampus ( In cases of severe thiamine deficiency, however, a broad enzymatic deficiency encompassing all three mitochondrial TPP-dependent enzymes would be expected to result in symptoms similar to those of the genetic disorder dihydrolipoamide dehydrogenase (DLDD) deficiency (OMIM 246900)

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