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Description
Acetyl-L-carnitine and/or liposomal co-enzyme Q10 prevent propionic acid-induced neurotoxicity by modulating oxidative tissue injury, inflammation, and ALDH1A1-RA-RAR signaling in rats
This potential is posited to be mediated via the MC4 receptors, which might even promote neurite outgrowth and possibly support the intrinsic capacity of neuronal tissue to recover after injury
Therefore, acetylcarnitine activities observed in vitro do not always represent pharmacological effects that could be achieved by acetylcarnitine supplementation in humans
JamilianHJamilianMSamimiMAfshar EbrahimiFRahimiMBahmaniFet al
