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10.1016/j.chembiol.2016.07.020 Cell Chem
Systemic side effects are uncommon but can include mild nausea if administered on an empty stomach (take with food), flushing from high-dose B12 (benign and self-limiting), and rarely allergic reactions to preservatives in the formulation
doi: 10.1016/S2666-7568(21)00086-6
Mol Neurodegener 8(1):22
