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Q.et al (2009a)
77 On the other hand, in two similar studies using a preclinical canine IVD degeneration model, the intradiscal delivery of either nonsteroidal (celecoxib, selective COX2 inhibitor) or steroidal antiinflammatory (triamcinolone acetonide) drug release by a microsphere platform was able to reduce NGF expression in the IVD
J Pain Symptom Manage 2017;54:916
This approach has many inherent advantages, and represents the method of choice, particularly if it can be used for the early diagnosis of renal lesions or dysfunction in experimental animals being used for nephrotoxicity screening studies
