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Thus, tau hyper-phosphorylation is another neuropathologic hallmark of AD and is linked to microglia activation and neuronal damage (Medeiros et al., 2010

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"A double-blind, randomized phase II study to evaluate the safety and efficacy of acetyl-L-carnitine in the prevention of sagopilone-induced peripheral neuropathy." Oncologist 18(11): 1190-1191

All the evidence related to cuproplasia and cuproptosis is derived from retrospective studies, with only the association between reduced copper levels and a higher risk of lung cancer stemming from a meta-analysis of retrospective data
