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WHO Collaborating Centre for Drug Statistics and Methodology

ESA, Inc.)

If immunotherapy aims to establish protective immune memory comparable to that induced by acute infection, then its failure to do socoupled with the insufficient tumor-killing capacity that permits on-treatment progressionreveals fundamental limitations in current strategies and underscores the need for a mechanistic explanation

doi: 10.1016/s0891-5849(00)00317-8
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