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However, because HF in diabetes currently occurs more frequently as HFpEF than HFrEF, we assume that a reasonable proportion of HF events in this study were actually HFpEF

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However, contrary to the tumor-promoting potential of many angiogenic agents, BPC-157 has been shown to inhibit uncontrolled cell proliferation, downregulate VEGF expression, and counteract VEGF-driven tumorigenesis, including suppression of Ki-67 and VEGF pathway activation [31, 73]

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