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The bloodbrain barrier in health and Disease: important unanswered questions
LoPE, also referred to as maternal preeclampsia, is associated with a mismatch between the increasing metabolic demands of the placentafoetal duet and the normal maternal perfusion, contributing to a maternal predisposition to cardiovascular and metabolic pathologies

Poewe W, Seppi K, Tanner CM, Halliday GM, Brundin P, Volkmann J, et al

They are difficult for the liver to process