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This weight loss is noteworthy because it occurred in subjects with type 2 diabetes, on concomitant insulin therapy, and in the face of a significant A1C reduction, factors that all favor weight gain

Gut-related benefits generally show up in two to four weeks instead of days

One hundred type 2 diabetes mellitus patients on metformin 4 months with vitamin B12 deficiency were enrolled in this study and randomized equally into two groups

Some are FDA-approved for the treatment of obesity, while others are used off-label
