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Typical autoimmune diseases have characteristic pathogenic IgGs correlated with inflammation, tissue injury, and complement activation

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Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials
LCN2 is an iron trafficking protein that acts as a major driver of post-traumatic neuroinflammation, and genetic inactivation of Lcn2 or LCN2 depletion reduced brain damage and improved neurological outcome after TBI 88,89
