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Effects on mitochondrial function in tissues like skeletal muscle have been observed within hours, but structural and functional benefits in conditions like AMD, Barth, and kidney disease typically take months of continuous dosing

While vitamin B12 injections are commonly recommended for individuals with a diagnosed deficiency or those at risk of deficiency due to certain medical conditions or dietary restrictions, they can also benefit: Vegetarians and Vegans : Plant-based diets may lack sufficient sources of vitamin B12, making injections a valuable option for keeping optimal levels

10.1074/jbc.ra118.001764 J