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Copper Chelation and Delivery At the most fundamental level, GHK functions as a copper chelator and delivery system - the tripeptide binds Cu with exceptionally high affinity (binding constant approximately 10 M, among the highest known for biological copper chelators), forming a square planar coordination complex where the copper ion is coordinated by the nitrogen atoms of the terminal amino group, the two peptide bonds, and the imidazole nitrogen of histidine

Then, Logistics regression was performed to identify the predicted value of SOD and GR for survival and free walking abilities at 6 months and 1 year after surgery

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Contributory factors in addition to, or likely due to the described effect on vessel recruitment [20,21,22,23,24,25,26,27], may be that BPC 157 counteracts in rats various encephalopathies [33,34,35,36,37,38,39,40,41]