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What was important about Burnet's theory was not only that he introduced the idea of clonal selection, but also the 'concept of a randomization mechanism to generate initial diversity of specificity' (Hodgkin, Heath, Baxter)

Oxidative damage is the main factor affecting RBC storage lesion which is caused by free radicals

Figure 2 Therefore, nutrients have an essential role in the defense function of mammals

Additionally, inhibition of PKCs with enzastaurin and of MAPK signaling with U0126 and GW5074 also abolished NET formation (Extended Data Fig
