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The participant was positioned prone, and the heel was placed in a neutral position on the edge of the examination bed to prevent tension in the tendons or muscles

Nevertheless, IGF-I mRNA abundance is reduced in the brain of hypophysectomized rats and, intracerebral infusion of GH restores IGF-I mRNA to 80% of normal levels[70], which points out that GH has a clear role in modulating brain IGF-I

For individuals with absorption difficulties, digestive conditions, or diagnosed deficiency, injections may be more appropriate than oral supplements

doi: 10.1111/j.1600-6143.2009.02813.x 54 GloorJMWintersJLCornellLDFixLADeGoeySRKnauerRMet al