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Description
Sunitinib Sunitinib (Sutent ) is a novel oral multitargeted TKI of VEGFR-1, VEGFR-2, fetal liver tyrosine kinase receptor 3, c-KIT, PDGFR-, and PDGFR- (Yardley et al., 2012)

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Phase 2 combination trials reported 35-40% discontinuation rates due to GI side effects when both agents were dosed simultaneously

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