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In this same pathway of sulfur amino acids, HCY can be metabolized producing glutathione (GSH) ( Figure 1 ) ( IL1B and CCL3 also play a central role in the pathophysiology of COVID-19 ( Figure 1 The hypothesis of this study is that, during the advanced phase of COVID-19, characterized by hyperinflammation (cytokine storm), supplemental vitamin B12 would increase the flow of the sulfur amino acid pathway, favoring the production of SAM and the antioxidant GSH

Combining both compounds in a single capsule allows researchers to study their complementary effects on the NAD+ pathway within a single protocol

However, these surgeries also come with certain nutritional challenges that need to be carefully managed

Upon completing the four weekly doses, laboratory results demonstrated further improvement