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Description
The insulin and insulin-like growth factor-I receptor substrate IRS-1 associates with and activates phosphatidylinositol 3-kinase in vitro

The presence of double bonds, a carbonyl group, and hydroxyl groups within the C ring serves as the basis for their classification into various subclasses

1.0441

Ann Transl Med 6:467 Higgins T, Chaykin S, Hammond KB, Humbert JR (1972) Trimethylamine N-oxide synthesis: a human variant
