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doi: 10.1529/biophysj.108.137224 65 WangY-LKuoJ-HLeeS-CLiuJ-SHsiehY-CShihY-Tet al

Latest metabolic screening has shown a preferred accumulation of many metabolites and overexpression of genes of glutamine synthesis (glutaminolysis) pathways (e.g., glutamate, alpha-ketoglutarate (AKG), Glutamic pyruvate transaminase (GPT2), and Glycine amidinotransferase (GATM)) in IL-4-induced M2 macrophages (Biswas 2015)
As a result, it was recently reported that primordial germ cell-like cells were generated in vitro from pluripotent stem cells (PSCs) of rats, albeit a decade later than in mice 36

Addiction 88 (6), 791804
