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Conversely, impaired vagal activity reduces heart rate variability (HRV)a biomarker of cardiac autonomic integrity (Billman et al., 2015)which correlates with myocardial infarction and heart failure risk (Sessa et al., 2018
GSH, also known as glutathione, possesses the ability to undergo oxidation, thereby contributing to the maintenance of redox homeostasis
Indeed, neither moderate coffee intake (2 cups/day) nor coffee enemas (3x/week) showed any antioxidant-enhancing effects in a clinical trial on 11 healthy men [57]
However, this explanation would not be expected to apply to the wild type
