glutathione reductase catalytic mechanism cycle of P. falciparum Redox Regulation by Protein S-Glutathionylation:
Description
This means that rare adverse effects occurring outside controlled trial settings would not be systematically documented

Taken together, these data show that HCF101 is required in the assembly and transfer of 4Fe-4S (Figure 4A), but not classic or Rieske-type 2Fe-2S (Lezhneva et al., 4B)

(2) DHODH: DHODH is a mitochondrial flavoprotein localized to the inner mitochondrial membrane, where it catalyzes the fourth and rate-limiting step of de novo pyrimidine biosynthesisthe oxidation of dihydroorotate to orotate 42,43

Link et al., 2025)