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for serotonin a 4-5 fold increase has been reported, (8 by prostacyclin under prolonged hypoxia via reducing reactive oxygen species level in endothelial cells

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[9] It may often go unrecognized, as the body becomes used to feeling unwell

Patients with RP show a significant reduction in the GSH/GSSG ratio in the aqueous humor, and a significant increase in protein carbonyl content, suggesting oxidative stress and oxidative damage in the eyes of these patients [195]