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In the context of the immune system, optimal glutathione levels are essential for the maintenance of a redox-balanced environment for the proper functioning of lymphocytes and macrophages [6,7]

and trial design factors (endpoint selection, follow-up length)

Adair JC, Knoefel JE, Morgan N

Effects of sEH inhibitors on the vasculature are generally presumed to be due to local inhibition of vascular EET metabolism, as EETs can be produced and metabolized by blood vessels
