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2.4 Statistical Analysis of 16S rRNA Sequencing Data Following bioinformatic decontamination, ASVs and their corresponding taxonomy were plotted and visualized with the R packages phyloseq and vegan packages [35, 36]

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Treatment with DNMT inhibitors such as 5-azacytidine and decitabine restores BCL-2 methylation, reactivating apoptotic pathways and improving chemosensitivity (Wong et al., 2019
