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The TGA codon, encoding Sec, is found in the first exon of the human GPx-1 gene at amino acid 48 (of about 203 total), and it is located 105 nucleotides from the splice junction, suggesting that the GPx-1 gene transcript may be susceptible to nonsense-mediated decay

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CJEM 12: 449452, 2010 [DOI] [PubMed] [Google Scholar] 24.Lawrence DT, Bechtel LK, Charlton NP, Holstege CP: 5-oxoproline-induced anion gap metabolic acidosis after an acute acetaminophen overdose

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