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In contrast, orally ingested l-arginine is subject to moderate-to-high rates of first-pass extraction both in intestine and liver, likely due to their high expression of arginase [32,33,34], increasing arginine catabolism and limiting systemic increases in circulating levels following its ingestion [8]

Early improvement as a predictor of later response to antipsychotics in schizophrenia: a diagnostic test review

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Glutathione is an important antioxidant in the lungs, but its concentration is low in the airways of patients with cystic fibrosis, since GSH is transported into the airways by the cystic fibrosis transmembrane conductance regulator, which is mutated in cystic fibrosis patients (111)