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Some examples: Anticholinergic signs: dilated pupils, sweating, warm and red peripheries for example tricyclic antidepressant or belladonna alkaloid self-poisoning Sympathomimetic signs: tachycardia, high blood pressure, sweating, dilated pupils overdose of sympathomimetics, for example, amphetamines Increased respiratory rate, sweating and tinnitus salicylate self-poisoning Bradycardia and hypotension calcium channel blocker or beta-blocker self-poisoning Depressed respiration, consciousness and small pupils opioids (pinpoint pupils) or benzodiazepines self-poisoning Hyperthermia and rigidity selective serotonin reuptake inhibitors (SSRIs) Hypoglycaemia self-poisoning with anti-diabetic medications Key Actions Assess and Stabilise the Patient Drug overdose should be treated as a medical emergency

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(2005) Cell , 123 , 1337-1349

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Goal representations and motivational drive in schizophrenia: the role of prefrontalstriatal interactions

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