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Acknowledgements This research was funded by the Guangdong Provincial Department of Education as a scientific research project (2024KQNCX133), Zhanjiang Marine Youth Talent Project (2024R3004), the National Natural Science Foundation of China (82103834) and the Innovative Research Group of Functional Food Development and Quality Analysis (ZY24PYTD05)

Dosages may vary based on patient needs and provider protocol

The post hoc analysis of pooled data from the Semaglutide Treatment Effect in People with Obesity (STEP) 1, 2, 3, and 5 trials indicated that semaglutide treatment at 2.4 mg did not increase the risk of depressive symptoms or suicidal ideation compared to placebo, while demonstrating a statistically significant yet clinically negligible decrease in depressive symptoms [75]

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