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Increasing dietary fiber, staying well hydrated, and light daily movement like walking can address this effectively

The insulin signaling pathway is complex but requires the activation of Akt (a serinethreonine kinase) by phosphorylation [97]

On the other hand, cigarette smoke increases free radicals in our body

Cadmium-induced kidney dysfunction in our study was most likely the consequence of oxidant/antioxidant imbalance in the kidney, since it was parallel with elevated LPO and NO levels, which could be regarded as signals of increased generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS)