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Regardless of this limitation, it is worth noting that the majority of BMAd-secreted proteins and cytokines have negative effects on bone

J Strength Cond Res, 15(4), 486-90

Neuromuscul Disord 20: 4448, 2010

The presence of a substantially larger and charged residue in LPLA2 (Arg214) relative to LCAT (Gly230) may discourage the binding of bulkier acyl acceptors such as secondary alcohols and sterols