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yet penetrance is incomplete [6], perhaps resulting from environmental exposures

n = 23/108

Interleukin-1 receptor-associated kinase 1( IRAK-1 ) is a key downstream molecule of the TLR4 pathway, and its phosphorylation can activate a series of inflammatory pathways (84, 85), but in experiments, it was detected that CGA down-regulated the expression of TLR4 in the liver of mice exposed to ConA, and inhibited IRAK-1 , NF-B, and mitogen-activated protein kinase ( MAPK )

2,3-diketo-L-gulonic acid (2,3-DKG) is the further degradation product of DHA, and a heightened level of 2,3-DKG has been shown to be related to increased cataractogenesis in vivo (55)