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Description
The failure of Lys487 to form hydrogen bonds with Arg264 in its own subunit (or with Arg475 in its dimer subunit) results in a weaker NAD + binding site, a situation that ultimately affects the kinetic properties of the enzyme (Larson et al., 2007)

They work well for treating both deep pigmentation and overall skin lightening

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Beyerstedt, S., Casaro, E