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These novel mitochondrial-targeted agents show substantial promise in the treatment of CRC

By contrast, intracellular degradation enzyme ChaC1, differentially expressed in tumor cells, serves as a pro-apoptotic molecule by downregulating intracellular GSH levels under amino acid linkage and ER stress (99)

Brain targeting efficiency of antimigrain drug loaded mucoadhesive intranasal nanoemulsion

503 Despite these advances, the use of first- and second-generation mTOR inhibitors has been associated with a range of side effects such as insulin resistance, hyperglycemia, impaired wound healing, hypertension, and various metabolic, renal, and pulmonary complications