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Description
Shimizu, E

doi:10.1186/s40834-017-0050-9

A total sample size of 40 was chosen because it had greater than 80% power to detect a 4-point difference between groups in Montgomery-Asberg Depression Rating Scale (MADRS) scores over 12 weeks, assuming a standard deviation for repeated measures of MADRS of 6, and a within-subject correlation of 0.6

A randomized placebo controlled trial in which MCT was given to subjects with mild and moderate AD for 90 days increased serum concentrations of KB and improved cognitive functioning (145)
