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Given that the BP patients in the present study experienced psychosis, GSH may be involved in psychosis-associated pathophysiology that is shared by both SZ and BP

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7 Although the mechanism of NNMT in tumorigenesis remains to be delineated, upregulation of NNMT enzymatic activity has been suggested to lower the SAM/SAH ratio and alter the epigenetic landscape in cancer cells, as its expression level is inversely proportional to the SAM/SAH ratio

These differences may also explain differences in gastrointestinal adverse reactions, such as nausea and vomiting, which are common with GLP-1RAs but typically diminish over time [127, 128]