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doi: 10.1002/mrm.1910390515

Primary prevention of cardiovascular disease: A review of contemporary guidance and literature

In fact, many studies demonstrated that TMAO-induced NF-B activation is a significant downstream process that upregulates monocyte adhesion through upregulation of cellular adhesion molecules such as VCAM-1, but also intercellular adhesion molecule 1 (ICAM-1) and E-selectin, and enhances endothelial dysfunction [14,15]

Thus in the absence of CUP-5, there is an apparent mixing of content of lysosomes and of yolk granules, while the gut granules remain discrete and separate compartments
