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10.1038/s41467-024-52061-7 317 ZhouY.ZhangY.ZhaoD.YuX.ShenX.ZhouY.et al (2024b)

Similarly, NAD + levels appear reduced in preclinical models of age-associated diseases, including ataxia-telangiectasia (A-T), mitochondrial myopathies, and Alzheimers disease (AD), and disease-matched clinical samples 114,242,243,244,245,246
Autoimmune conditions are hypothesized to occur through exacerbation of the immunoregulatory deficiency

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