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hCG directly stimulates Leydig cells to produce and release intratesticular testosterone by binding to the luteinizing hormone/choriogonadotropin receptor (Rizzuti et al., 2023)

Those same actions especially the slowed stomach emptying are what drive nausea, and the gut adapts to them only gradually

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5-Amino-1MQ (5-Amino-1-methylquinolinium) is a novel small molecule peptide classified as an NNMT inhibitor meaning it blocks the activity of the enzyme nicotinamide N-methyltransferase (NNMT), which plays a key role in cellular energy metabolism , fat storage , and aging